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An effort that is inconvenient
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A source of difficulty
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An event causing distress or pain
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An angry disturbance
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A strong feeling of anxiety
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An unwanted pregnancy
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Cause bodily suffering to and make sick or indisposed
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Disturb in mind or make uneasy or cause to be worried or alarmed
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Move deeply
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To cause inconvenience or discomfort to
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Take the trouble to do something; concern oneself