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The supreme effort one can make
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The person who is most outstanding or excellent; someone who tops all others
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Canadian physiologist (born in the United States) who assisted F. G. Banting in research leading to the discovery of insulin (1899-1978)
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Get the better of
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(superlative of `good') having the most positive qualities
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It would be sensible
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In a most excellent way or manner
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From a position of superiority or authority
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(comparative and superlative of `well') wiser or more advantageous and hence advisable